AKESO (09926.HK) -3.900 (-3.662%) Short selling $1.01B; Ratio 24.511% announced the results of its HARMONI-6 clinical trial. Stretching last Friday (29th)'s rally, the stock opened 9.23% higher today (1st) and once spiked 12.3% to a peak of HKD132.6 in early trading. With gains later narrowed, it last quoted at HKD124.1, up 5.08%, with turnover surging to 31.5814 million shares, involving HKD3.961 billion.Nomura published a research report stating that AKESO announced encouraging results from the HARMONI-6 clinical trial, boosting sentiment across the sector and casting a strong positive impact for both the company and the industry. The broker believed the successful data from HARMONI-6 increases the probability of success for the HARMONI-3 clinical trial. It upgraded AKESO from Neutral to Buy, while slightly lowering the TP to HKD142.5 from HKD142.75.Related News CICC: Focus on Positive Capital Flow Impact from Index Review on BEONE MEDICINES (06160.HK), J&T EXPRESS-W (01519.HK), KNOWLEDGE ATLAS (02513.HK) and MINIMAX-W (00100.HK)Jefferies also noted that data from the HARMONI-6 China clinical trial showed an overall survival (OS) hazard ratio (HR) of 0.66, notably better than expected. Ivonescimab recorded a median overall survival (mOS) of 27.9 months, with survival benefits widening over time and remaining consistent across different PD-L1 expression subgroups. Meanwhile, no new safety signals were identified in the clinical trial. The broker maintained its Buy rating and TP of HKD226 on the company. (HK stocks quote is delayed for at least 15 mins.Short Selling Data as at 2026-06-02 16:25.)
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