HBM HOLDINGS-B (02142.HK) +0.080 (+0.628%) Short selling $5.99M; Ratio 16.773% announced that it has obtained approval from the US Food and Drug Administration (FDA) for its Investigational New Drug (IND) application and will initiate a first-in-human Phase I clinical trial in the United States for its novel B7H4xCD3 bispecific antibody HBM7004. The Phase I study will evaluate the safety, tolerability, pharmacokinetic profile and preliminary anti-tumor activity of HBM7004 in patients with advanced solid tumors.HBM7004 is a novel B7H4xCD3 bispecific antibody developed using the Groups proprietary HBICE?platform, offering differentiated solutions for cancer immunotherapy in terms of both efficacy and safety.
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