HENGRUI PHARMA (01276.HK) -3.750 (-4.756%) announced the signing of strategic cooperation agreements with GSK, granting GSK an exclusive worldwide right excluding Mainland China, Hong Kong, Macau and Taiwan, to its innovative drug PDE3/4 inhibitor HRS-9821 for the treatment of chronic obstructive pulmonary disease (COPD), as well as options for up to 11 early-stage programs in oncology, respiratory and immunology fields.Pursuant to the agreement, HENGRUI PHARMA will receive an upfront payment of US$500 million. If all programs are successfully developed and commercialized, the potential total amount could reach approximately US$12 billion, along with tiered royalties on global product net sales.(HK stocks quote is delayed for at least 15 mins.)Related NewsG Sachs: Easing CN-US Trade Tensions/ Other Factors Boost A-shr Indices to New Highs; MSCI China Index Target Raised to 90